Archive for February 5th, 2008

Can Soft Drinks Cause GOUT?

February 5, 2008

Another blow to the soft drinks industry published recently in the British Medical Journal January 31, 2008:

The study showed the risk of developing gout from drinking too much sweetened soda is increased but not with drinking diet soda.  It is the fructose in the drinks that is linked to increase uric acid level which is absent with diet drinks.


Results During the 12 years of follow-up 755 confirmed incident cases of gout were reported. Increasing intake of sugar sweetened soft drinks was associated with an increasing risk of gout. Compared with consumption of less than one serving of sugar sweetened soft drinks a month the multivariate relative risk of gout for

  • 5-6 servings a week was 1.29 , meaning a 29% increased risk! 
  • for one serving a day was 1.45, meaning a 45% increased risk!
  • for two or more servings a day was 1.85, meaning  an 85% increased risk!
  • Diet soft drinks were not associated with risk of gout.
  • total fruit juice or fructose rich fruits (apples and oranges) were also associated with a higher risk of gout (P values for trend <0.05).

Conclusions Prospective data suggest that consumption of sugar sweetened soft drinks and fructose is strongly associated with an increased risk of gout in men. Furthermore, fructose rich fruits and fruit juices may also increase the risk. Diet soft drinks were not associated with the risk of gout.


We seldom consider fructose as a culprit since we are used to looking at foods high in protein or purine like red meat or organ meats to be responsible for gout. The pathway at which fructose increases uric acid has not been given much importance until now!

For Gout: Soda is No Better than Beer!